If you are on this page, probably you are suffering this “ there is no disk in the drive” issue and try to figure it out. The remaining drive letters can be assigned to other disk partitions, removable devices and mapping network drives in accordance with actual demands. Generally, drive letter A: is allocated to the first floppy disk drive, B: to the second floppy disk drive, and C: to the first disk partition where the running Windows is installed.Select the new drive letter, select OK, and then select Yes when prompted about how programs that rely on the drive letter might not run correctly. To add a drive letter if the drive doesn't already have one, select Add. To change the drive letter, select Change.Some Programs That Rely On Drive Letters Sample.Changing the drive letter means that the program cannot find itself and will then refuse to run.
For example, older software may always insist that the optical drive have the same letter now as it did when the program was installed. Some programs rely on consistent drive letters.